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Polio serology

Alias: N/A

Discipline: Clinical Microbiology

Test information: Approved indications for polio serological testing: Diagnosis of poliovirus infection when the diagnosis cannot be established by molecular or culture-based methods, by comparing titres in acute and convalescent sera. Serological confirmation of poliovirus infection following detection of poliovirus using molecular and/or culture-based assays. Quantifying antibody levels in individuals who work in laboratories where there is deliberate handling of poliovirus. Excluded indications (samples will not be processed): Demonstrating an antibody response to polio vaccination to assist in the diagnosis of immunodeficiency states including, but not limited to, primary humoral immunodeficiencies.

Specimen Type(s)
  • Blood;
Other Acceptable Specimen Type(s)
Specimen Container - Adult
  • Gold Top SST BD;
Specimen Container - Paediatric
  • N/A;
  • N/A;
Part of a test profile?
Volume (min) of sample to be sent to laboratory
Patient Preparation, Sample Handling and Transport
Minimum-clotting time 30 minutes. Do not send grossly haemolysed specimens. Specimens should be transported to the laboratory as soon as possible. Outside of normal hours samples should be refrigerated (2 °C to 8 °C).
Maximum add on time
Units and Reference Ranges / Interpretation
Non-reactive / Reactive
UKAS number
UKAS accredited test?
Detecting antibodies or quantifying antibody levels in individuals travelling to an overseas area that has an active polio outbreak.

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Last updated: 24-07-2024