Anti-Streptococcal Serology

Test information: ASO (Anti-Streptolysin O) and Anti-DNase B ( Anti-Streptodornase B) are tests used to diagnose recent streptococcal infection in post-streptococcal conditions, such as glomerulonephritis and rheumatic fever.

Availability: Referred to Royal Devon and Exeter NHS Foundation Trust: Monday - Friday during routine hours: 08:45 - 17:15.

Turnaround Time: 2 - 16 Days upon receipt at Royal Devon and Exeter NHS Foundation Trust.

Specimen Type(s)

• Clotted blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Gold Top SST BD;

Specimen Container - Paediatric

• Plain Top Sarstedt;

Analytes

• Anti-DNase B;
• Anti-Streptolysin O;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

4mL Clotted Blood

Patient Preparation, Sample Handling and Transport

• Minimum-clotting time 30 minutes.
• Specimens should be transported to the laboratory as soon as possible.
• Outside of normal hours samples should be refrigerated (2 °C to 8 °C).

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

Anti-streptolysin O: Screening titre <1/200 units.

Anti-DNAse B: Screening titre <1/200 units.

Comment: Positives are consistent with recent streptococcal infection and are most likely to be Group A, C, or G streptococci.

UKAS number

9018

UKAS accredited test?

Yes

Comments

N/A

If you have any queries about a test or results interpretation please contact us.