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Amoebic Serology

Alias: Entamoeba histolytica, Entamoeba dispar, Amoebic Liver Abscess (ALA)

Discipline: Virology

Test information: Is an essential test in cases of suspected amoebic liver abscess (ALA).

Availability: Referred to Hospital for Tropical Disease, Health Services laboratories (HSL): Monday - Friday during routine hours: 08:45 - 17:15.

Turnaround Time: 28 Day upon receipt at Hospital for Tropical Disease

Specimen Type(s)
  • Clotted blood;
Other Acceptable Specimen Type(s)
Specimen Container - Adult
  • Gold Top SST BD;
Specimen Container - Paediatric
  • N/A;
  • Entamoeba histolytica / Entamoeba dispar antibodies;
Part of a test profile?
Volume (min) of sample to be sent to laboratory
5mL Clotted Blood
0.5mL Serum
Patient Preparation, Sample Handling and Transport
  • Minimum-clotting time 30 minutes.
  • Specimens should be transported to the laboratory as soon as possible.
  • Outside of normal hours samples should be refrigerated (2 °C to 8 °C).
Maximum add on time
Units and Reference Ranges / Interpretation
Amoebic IFAT: Negative / Positive
UKAS number
UKAS accredited test?

Amoebic serology may be negative in amoebic dysentery, especially in the early stage. If clinical suspicion remains please send a further serum sample 2 weeks after the first sample. In addition, for all suspected cases of intestinal amoebiasis, faecal microscopy and PCR for Entamoeba histolytica should be performed.

Amoebic serology may take up to 2 weeks to become positive in amoebic liver abscess.

If you have any queries about a test or results interpretation please contact us.

Last updated: 02-06-2023