Screening for Lupus Anticoagulant
Alias: N/A
Discipline: Coagulation
Test information: To help evaluate a prolonged activated partial thromboplastin time (aPTT) and/or a thrombotic episode, to help determine the cause of recurrent fetal loss, as part of an evaluation for antiphospholipid syndrome. Not a diagnostic test for lupus (SLE).
- Specimen Type(s)
-
- Blood;
- Other Acceptable Specimen Type(s)
- N/A
- Specimen Container - Adult
-
- Light Blue Top BD;
- Specimen Container - Paediatric
-
- N/A;
- Analytes
-
- N/A;
- Part of a test profile?
- No
- Volume (min) of sample to be sent to laboratory
- 4ml
- Patient Preparation, Sample Handling and Transport
- Patients on heparin or heparin substitute (such as hirudin, danaparoid, or argatroban) anticoagulation therapy may have false-positive results for lupus. To be transferred to laboratory within 4 hours to minimise platelet activation and neutralisation of any lupus anticoagulant. Please make a note of any anticoagulants and/or bleeding/bruising symptoms.
- Maximum add on time
- N/A
- Units and Reference Ranges / Interpretation
- Screen Ratio greater than 2.0 - LA is strongly present, Screen Ratio between 1.5-2.0 - LA is moderately present, Screen Ratio between 1.2-1.5 - LA is weakly present
- UKAS number
- 8869
- UKAS accredited test?
- Yes
- Comments
- Direct-acting oral anticoagulants (DOACs) give false positive results.
If you have any queries about a test or results interpretation please contact us.
Last updated: 30-01-2023