Thrombophilia

Test information: Thrombophilia screening should start with an affected relative. Current guidelines advise screening other family members only if a defect is identified in a first degree relative. Thrombophilia screening should be performed when a patient is stable (unless clinically urgent), even if on Warfarin, as results can be unsatisfactory if performed close to an event, due to the acute phase response.

Specimen Type(s)

• Blood;

Other Acceptable Specimen Type(s)

3 x blue top citrate sample (blue tube 3.2% tri-sodium citrate). 1 X Purple top EDTA sample for Full blood count 1x Gold top serum tube for anti-cardiolypin.

Specimen Container - Adult

• Light Blue Top BD;

Specimen Container - Paediatric

• N/A;

Analytes

• N/A;

Part of a test profile?

Thrombophilia screen

Volume (min) of sample to be sent to laboratory

4ml

Patient Preparation, Sample Handling and Transport

Completion and submission of a Thrombophilia Investigation Sheet and sent with accompanying samples will speed appropriate testing and return of results - please contact lab directly on 01872 25 (2502) if a copy is required.

Maximum add on time

4 hours

Units and Reference Ranges / Interpretation

Linear range: Antithrombin 7.2-150%, Protein C 5-120%, Proteins S 7.3-150 All thrombophilia results outside normal ranges are referred to Consultant Haematologist for review.

UKAS number

8869

UKAS accredited test?

Yes

Comments

Please note- Prothrombin Gene mutation is often tested as part of a wider thrombophilia investigation, it is not an accredited test.

If you have any queries about a test or results interpretation please contact us.