Glucose (CSF)

Test information: CSF glucose or glycorrhachia is a measurement used to determine the levels of glucose in cerebrospinal fluid. Normal levels are about 2/3 the concentration of blood glucose. Glucose levels may decrease when cells that are not normally present metabolise the glucose. These may include bacteria or cells present due to inflammation (WBCs) or shed by tumours. CSF glucose will therefore be decreased in bacterial meningitis, tuberculous meningitis and subarachnoid haemorrhage. Glucose levels are usually within normal limits in viral or aseptic meningitis.

Specimen Type(s)

• Cerebrospinal fluid;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Plain Universal;

Specimen Container - Paediatric

• Plain Universal;

Analytes

• N/A;

Part of a test profile?

N/A

Volume (min) of sample to be sent to laboratory

1ml

Patient Preparation, Sample Handling and Transport

Fraction 2 is sent to Clinical Chemistry for protein and glucose assay. A bllod glucose should also be measured.

Maximum add on time

Same day protein. Glucose not allowed

Units and Reference Ranges / Interpretation

RR for Males and Females - mmol/L Less than 19 years - 3.3 to 4.5 “CSF glucose should be interpreted in relation to plasma glucose. The normal CSF/plasma glucose ratio is approximately 0.6” 19 years and above - 2.2 to 3.9 “CSF glucose should be interpreted in relation to plasma glucose. The normal CSF/plasma glucose ratio is approximately 0.6”

UKAS number

8869

UKAS accredited test?

Yes

Comments

Analysis should be undertaken promptly because glucose metabolism continues after the sample has been aspirated.

If you have any queries about a test or results interpretation please contact us.