Circulating tumour blood testing (ctDNA) for EGFR

Test information: Blood samples for CtDNA can be sent to cytology for the assessment of EGFR driver mutation status or T790M resistance in patients with known lung adenocarcinoma or patient suspected of advanced lung carcinoma that are unable to go any interventional procedure

Specimen Type(s)

• Blood;

Other Acceptable Specimen Type(s)

Purple EDTA tubes. Ensure sample vial is labelled with specimen site / type

Specimen Container - Adult

• Purple Top BD;

Specimen Container - Paediatric

• Purple Top Microtainer BD;

Analytes

• N/A;

Part of a test profile?

N/A

Volume (min) of sample to be sent to laboratory

4 tubes

Patient Preparation, Sample Handling and Transport

The cytology department must be contacted before the sample is taken. Samples are collected into 4 purple EDTA tubes. The request form must contain the reason for the request (T790M / unable to obtain tissue). Hand delivered to a member of the cytology team within 1 hour. Sample vials must be placed into a clear sealed specimen bag prior to sending to the laboratory accompanied with a completed request form. The sample must be transported to the department using the red designated Pathology transport boxes. These boxes will contain any spillage, and ensure data on samples is kept confidential. Specimens should never be placed in pockets, handbags etc.

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

Interpretative comments

UKAS number

8869

UKAS accredited test?

Yes

Comments

N/A

If you have any queries about a test or results interpretation please contact us.