HIV-1 Proviral Tropism Testing

Test information: Tropism assays are used to determine co-receptor usage of HIV-1 in patients who may be candidates for treatment with CCR5 antagonists. Tropism testing is strongly recommended in all patients who have virological failure for whom a CCR5 antagonist is being considered as part of the subsequent treatment.

Availability: Referred to UK Health Security Agency (UKHSA) the antiviral unit (AVU): Monday - Friday during routine hours: 08:45 - 17:15.

Turnaround Time: 21 Days upon receipt at UK Health Security Agency (UKHSA) the antiviral unit (AVU)

Related Tests:

• Human Immunodeficiency Virus Serology
• Human Immunodeficiency Virus Viral Load
• HIV-1 Genotypic Resistance Testing
• Recent Infection Testing Algorithm (RITA)

Specimen Type(s)

• EDTA Whole Blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Purple Top BD;

Specimen Container - Paediatric

• N/A;

Analytes

• N/A;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

Whole Blood: 10 - 20mL
Please note this test requires > 1 mL of plasma to perform.

Patient Preparation, Sample Handling and Transport

• Specimens should be transported to the laboratory as soon as possible
• Whole blood samples are stable up to 24 hours at 2 - 30 °C

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

Reference report sent directly to requestor.

UKAS number

8197

UKAS accredited test?

Yes

Comments

N/A

If you have any queries about a test or results interpretation please contact us.