Cryptococcus Serology

Test information: Diagnosis of infection with Cryptococcus neoformans typically associated with immunosuppression.

Availability: Referred to Severn Pathology North Bristol NHS Trust: Monday - Friday during routine hours: 08:45 - 17:15.

Turnaround Time: 3 Days upon receipt at Severn Pathology North Bristol NHS Trust

Specimen Type(s)

• Cerebrospinal fluid;
• Clotted blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Gold Top SST BD;
• Sterile CE-marked Universal Container;

Specimen Container - Paediatric

• Plain Top Sarstedt;
• Sterile CE-marked Universal Container;

Analytes

• Cryptococcal antigen;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

Blood 2.5 - 5mL
CSF Minimum 0.5mL

Patient Preparation, Sample Handling and Transport

• Minimum-clotting time 30 minutes.
• Specimens should be transported to the laboratory as soon as possible.
• Outside of normal hours samples should be refrigerated (2 °C to 8 °C).
• This test should only be requested when clinical evidence suggests the diagnosis of Cryptococcal disease. Please contact a consultant microbiologist.
• Please state the following date of onset of symptoms, any relevant clinical details and indicate type of immunosuppression.

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

Results: Negative / Positive
(NEAT specimen or titre given).

UKAS number

8043

UKAS accredited test?

Yes

Comments

N/A

If you have any queries about a test or results interpretation please contact us.