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D-Dimer

Alias: N/A

Discipline: Haematology

Test information: D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link, hence forming a protein dimer.
D-dimer concentration may be determined by a blood test to help diagnose thrombosis. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis, but does not exclude other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low.

Specimen Type(s)
  • Blood;
Other Acceptable Specimen Type(s)
N/A
Specimen Container - Adult
  • Light Blue Top BD;
Specimen Container - Paediatric
  • N/A;
Analytes
  • N/A;
Part of a test profile?
No
Volume (min) of sample to be sent to laboratory
4ml
Patient Preparation, Sample Handling and Transport
Coagulation samples are volume critical, if a patient is difficult to bleed paediatric tubes (1.3ml) are available on request.
Some patients with a grossly raised Haematocrit (HCT) >0.57 may give erroneous coagulation test results - individual patient adjusted volume coagulation tubes are available on request from the laboratory.
Maximum add on time
24 hours
Units and Reference Ranges / Interpretation
Pos/Neg
UKAS number
8869
UKAS accredited test?
Yes
Comments
N/A

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Last updated: 03-05-2024