Paracetamol

Test information: Paracetamol (acetaminophen) is a common drug used in many formulations due to its analgesic and antipyretic properties. Chronic excessive use of paracetamol can result in hepatotoxicity and nephrotoxicity. Over dosage can lead to severe hepatic damage and hepatic failure if untreated. Early diagnosis of paracetamol-induced hepatotoxicity is important since initiation of therapy within 16 hours of ingestion lessens the potential for hepatic injury and decreases the mortality rate. 

Specimen Type(s)

• Blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Gold Top SST BD;

Specimen Container - Paediatric

• Light Green Top Microtainer BD;

Analytes

• N/A;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

4ml

Patient Preparation, Sample Handling and Transport

Acute over-dose at least 4 hours post and staggered take sample immediately. For both see BNF/TOXBASE advice.

Maximum add on time

5 days

Units and Reference Ranges / Interpretation

mg/L

UKAS number

8869

UKAS accredited test?

Yes

Comments

N/A

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