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Alpha-1-Antitrypsin

Alias: A1AT, AAT

Discipline: Clinical Chemistry

Test information: Acute hereditary alpha-1-Antitrypsin deficiency is suspected in cases of neonatal hepatitis accompanied by progressive liver cirrhosis in early childhood. It is also suspected when severe pulmonary emphysema occurs in adults due to the prevalence of leucocyte elastase, which can lead to unrestrained proteolytic degradation of the pulmonary parenchymal cells.

Specimen Type(s)
  • Blood;
Other Acceptable Specimen Type(s)
N/A
Specimen Container - Adult
  • Gold Top SST BD;
Specimen Container - Paediatric
  • Clear - Plain;
Analytes
  • N/A;
Part of a test profile?
No
Volume (min) of sample to be sent to laboratory
4ml
Patient Preparation, Sample Handling and Transport
N/A
Maximum add on time
5 days
Units and Reference Ranges / Interpretation
RR for Males and Females
less than 19yrs - 1.10 - 1.81 g/L
19yrs & above - 0.90 - 2.00 g/L
UKAS number
8869
UKAS accredited test?
Yes
Comments
N/A

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Last updated: 03-05-2024