Calprotectin

Test information: Calprotectin is a calcium binding protein produced in cells such as neutrophils and is released during inflammation. Faecal calprotectin is a biomarker of intestinal mucosal inflammation; In the presence of an inflammatory bowel disease (IBD) neutrophils influx into the intestinal lumen and release calprotectin which is then excreted in faeces. Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) produce similar symptoms but have different treatment methods. The faecal calprotectin test can be used to help distinguish between the two conditions.

Specimen Type(s)

• Faeces;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Blue Top Container (Fecon);
• Plain Faecal Pot;

Specimen Container - Paediatric

• N/A;

Analytes

• N/A;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

A single random formed stool sample approx. 2 g (cherry-sized).

Patient Preparation, Sample Handling and Transport

NSAIDS can cause raised faecal calprotectin

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

30-1800 ug/L Interpretative comment provided

UKAS number

8869

UKAS accredited test?

Yes

Comments

N/A

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