Complement (C3 and C4)

Test information: The complement system is a cascading series of plasma proteins whose end-products cause bacterial lysis and remove the immune complexes found in post-streptococcal glomerulonephritis, SLE and other autoimmune disease.There is reduction of C3 in PSGN and of both C3 and C4 in SLE. They are increased in most other inflammatory states.

Specimen Type(s)

• Blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Gold Top SST BD;

Specimen Container - Paediatric

• Light Green Top Microtainer BD;

Analytes

• N/A;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

4ml

Patient Preparation, Sample Handling and Transport

N/A

Maximum add on time

5 days

Units and Reference Ranges / Interpretation

C3 - RR for Males and Females - less than 15 days - 0.50 - 1.21 - g/L RR for Males and Females - 15dys to less than 1 yr - 0.51 - 1.60 - g/L RR for Males and Females - 1yr to less than 19yrs - 0.83 - 1.52 - g/L RR for Female - 19yrs to 80 yrs - 0.83 - 1.93 - g/L RR for Male - 19yrs to 80 yrs - 0.82 - 1.85 - g/L C4 - RR for Males and Females - less than 1yr - 0.07 - 0.30 - g/L RR for Males and Females - 1yr to less than 19yrs - 0.13 - 0.37 - g/L RR for Female - 19yrs to 80yrs - 0.15 - 0.57 - g/L RR for Male - 19yrs to 80yrs - 0.15 - 0.53 - g/L

UKAS number

8869

UKAS accredited test?

Yes

Comments

N/A

If you have any queries about a test or results interpretation please contact us.