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Complement (C3 and C4)

Alias: C3 and C4

Discipline: Clinical Chemistry

Test information: The complement system is a cascading series of plasma proteins whose end-products cause bacterial lysis and remove the immune complexes found in post-streptococcal glomerulonephritis, SLE and other autoimmune disease.There is reduction of C3 in PSGN and of both C3 and C4 in SLE. They are increased in most other inflammatory states.

Specimen Type(s)
  • Blood;
Other Acceptable Specimen Type(s)
N/A
Specimen Container - Adult
  • Gold Top SST BD;
Specimen Container - Paediatric
  • Light Green Top Microtainer BD;
Analytes
  • N/A;
Part of a test profile?
No
Volume (min) of sample to be sent to laboratory
4ml
Patient Preparation, Sample Handling and Transport
N/A
Maximum add on time
5 days
Units and Reference Ranges / Interpretation
C3 -
RR for Males and Females
less than 15 days - 0.50 - 1.21 g/L
15dys to less than 1 yr - 0.51 - 1.60 g/L
1yr to less than 19yrs - 0.83 - 1.52 g/L
RR for Female - 19yrs to 80 yrs - 0.83 - 1.93 g/L
RR for Male - 19yrs to 80 yrs - 0.82 - 1.85 g/L
C4 -
RR for Males and Females
less than 1yr - 0.07 - 0.30 g/L
1yr to less than 19yrs - 0.13 - 0.37 g/L
RR for Female - 19yrs to 80yrs - 0.15 - 0.57 g/L
RR for Male - 19yrs to 80yrs - 0.15 - 0.53 g/L
UKAS number
8869
UKAS accredited test?
Yes
Comments
N/A

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Last updated: 03-05-2024