Thiopurine metabolites

Test information: Immunosuppression mediated primarily cytotoxic 6TGN & incorporation of these false bases into DNA. Accumulation of high levels of 6TGN is also responsible for some side effects and has been associated with leucopenia. High levels of the inactive metabolite 6MMPN may be associated with hepatotoxicity

Specimen Type(s)

• Blood;

Other Acceptable Specimen Type(s)

N/A

Specimen Container - Adult

• Purple Top BD;

Specimen Container - Paediatric

• Lilac Top Microtainer BD;

Analytes

• N/A;

Part of a test profile?

No

Volume (min) of sample to be sent to laboratory

2ml

Patient Preparation, Sample Handling and Transport

None.

Maximum add on time

N/A

Units and Reference Ranges / Interpretation

Please see the report.

UKAS number

8407

UKAS accredited test?

Yes

Comments

N/A

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